Tuesday, July 23, 2013

ANSI / NETA ATS Standard for Acceptance Testing Specifications for Electrical Power Equipment and Systems 2013 - Bound - Print Edition


ANSI / NETA ATS Standard for Acceptance Testing Specifications for Electrical Power Equipment and Systems 2013 - Bound - Print Edition

Prazo de entrega entre 3 a 4 semanas.

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

The NETA Acceptance Testing Specifications was developed for use by those responsible for assessing the suitability for initial energization of electrical power equipment and systems and to specify field tests and inspections that ensure these systems and apparatus perform satisfactorily, minimizing downtime and maximizing life expectancy. 

Use the ANSI/NETA ATS 2013 as a guide when specifying and performing the necessary tests to ensure that your electrical systems and apparatus not only meet your project specifications, but that the manufacturer of the equipment supplied you with a product that will perform safely and reliably for many years to come.

Acceptance tests are not manufacturers factory tests. They comprise those tests necessary to determine that the electrical equipment has been selected in accordance with the engineer's requirements, installed in accordance with applicable codes and installation standards, and perform in accordance with their design and setting parameters. The ANSI/NETA Standard for Acceptance Testing Specifications for Electrical Power Equipment and Systems assists designers, specifiers, architects, and users of electrical equipment and systems in specifying required tests on newly-installed power systems and apparatus, before energizing, to ensure that the installation and equipment comply with specifications and intended use as well as with regulatory and safety requirements.
 

1. GENERAL SCOPE 

1. These specifications cover the suggested field tests and inspections that are available to assess the suitability for initial energization and final acceptance of electrical power equipment and systems.

2. The purpose of these specifications is to assure that tested electrical equipment and systems are operational, are within applicable standards and manufacturer's tolerances, and are installed in accordance with design specifications.

3. The work specified in these specifications may involve hazardous voltages, materials, operations, and equipment. These specifications do not purport to address all of the safety issues associated with their use. It is the responsibility of the user to review all applicable regulatory limitations prior to the use of these specifications.

NBIC 2013 - National Board Inspection Code 2013 Edition (Three Volumes Set) / Published: July 2013 - Hardcopy - Versão Impressa


NBIC 2013 - National Board Inspection Code 2013 Edition (Three Volumes Set) / Published: July 2013 - Hardcopy - Versão Impressa

Lançamento: Julho de 2013

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Product Details

The 2013 Edition of the National Board Inspection Code (NBIC) will be available mid-July.
Weight: 8 lbs 8 ozs

NBIC National Board Inspection Code 2013 (NBIC 2013)covers boiler and pressure vessels and required for ASME stamp holders and repair firms as well as inspections.


The NBIC is an American National Standards Institute (ANSI) accredited standard and provides rules and guidelines for the installation, inspection, repair and alteration of boilers, pressure vessels and pressure relief devices. It is required in many United States and Canadian jurisdictions.


The NBIC has a long history of setting jurisdictional standards in North America from Cities, States and Canadian Providences.  The NBIC 2013 is an International Standard and as expressed a longtime North American National Standard.  

The NBIC 2013 is also known as the National Board Inspection Code  or the NBIC.  The NBIC 2013 edition replaces the NBIC 2011 edition.  Also, in 2011, the National Board of Boilers and Pressure Vessel Inspectors ceased the printing of  addendums. This is a great improvement from earlier NBIC editions, but in the pre-1990 the NBIC was one-book consisting of boiler and pressure vessel installations, then inspection of boilers and pressure vessels as well as the repair and alterations of boilers and pressure vessel.  The NBIC has come a long ways! 

Today, the National Board Inspection Code 2013 edition continues to provide the same vital information to users of boilers and pressure vessels as in past year NBIC editions.  As always, the new NBIC consist of the three parts: installation, inspection, and repairs and alterations. Each NBIC is bound. The National Board Inspection Code (NBIC) Parts:

Part 1 Installations of Boilers & Pressure Vessels
Part 2 Inspections of Boilers & Pressure Vessels
Part 3 Repairs and Alternations of Boilers & Pressure Vessels

The NBIC also known as the National Board of Boilers & Pressure Vessel Code is the premier post construction code book for boilers and pressure vessels worldwide and is constantly improving. 


Important Note: All National Board Stamp Holders are required to have the complete National Board Inspection Code (NBIC 2013) set.

DIN Handbook 362 Fasteners 6 - 2012-06 - 2. Edition - ISBN 978-3-410-22827-1 (63 Standards) - Dimensional standards for bolts and screws - European Standards - Translation: English


DIN Handbook 362 Fasteners 6 - 2012-06 - 2. Edition - ISBN 978-3-410-22827-1 (63 Standards) - Dimensional standards for bolts and screws - European Standards - Translation: English

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Publisher: DIN

Publication date 2012-06
2. Edition, 788 Pages, A5, Paper covers
ISBN 978-3-410-22827-1 

The 2nd edition of DIN Handbook 362 includes 60 European Standards (DIN EN and DIN EN ISO Standards) for dimensions of bolts and screws. Compared to the 1st edition 25 standards, especially those dealing with slotted head screws, hexagon head screws, cross recessed head screws and hexalobular socket head screws, have been revised. 15 standards (including DIN EN ISO 7380-2 and DIN EN ISO 12474 on hexagon socket head cap screws as well as three further parts of the DIN EN 14399 series on high-strength structural bolting assemblies) are new to this compilation.

63 Standards

DIN 918 Beiblatt 3 , Publication date: 2010-01Fasteners - Supplement 3: European Standards - Survey

DIN EN 1662 , Publication date: 1998-02Hexagon bolts with flange, small series (ISO/DIS 15071:1996, modified); German version EN 1662:1997

DIN EN 1662 Berichtigung 1 , Publication date: 2007-06Hexagon bolts with flange, small series (ISO/DIS 15071:1996, modified); German version EN 1662:1997, Corrigenda to DIN EN 1662:1998-02; German version EN 1662:1997/AC:2007

DIN EN 1665 , Publication date: 1998-11Hexagon bolts with flange, heavy series; German version EN 1665:1997

DIN EN 1665 Berichtigung 1 , Publication date: 2007-07Hexagon bolts with flange, heavy series; German version EN 1665:1997, Corrigenda to DIN EN 1665:1998-11; German version EN 1665:1997/AC:2007

DIN EN 14219 , Publication date: 2003-09Hexagon bolts with flange with metric fine pitch thread - Small series (ISO 15072:1999, modified); German version EN 14219:2003

DIN EN 14219 Berichtigung 1 , Publication date: 2007-06Hexagon bolts with flange with metric fine pitch thread - Small series (ISO 15072:1999, modified); German version EN 14219:2003, Corrigenda to DIN EN 14219:2003-09; German version EN 14219:2003/AC:2007

DIN EN 14399-3 , Publication date: 2006-06High-strength structural bolting assemblies for preloading - Part 3: System HR - Hexagon bolt and nut assemblies; German version EN 14399-3:2005

DIN EN 14399-4 , Publication date: 2006-06High-strength structural bolting assemblies for preloading - Part 4: System HV - Hexagon bolt and nut assemblies; German version EN 14399-4:2005

DIN EN 14399-7 , Publication date: 2008-03High-strength structural bolting assemblies for preloading - Part 7: System HR - Countersunk head bolt and nut assemblies; German version EN 14399-7:2007

DIN EN 14399-8 , Publication date: 2008-03High-strength structural bolting assemblies for preloading - Part 8: System HV - Hexagon fit bolt and nut assemblies; German version EN 14399-8:2007

DIN EN 14399-10 , Publication date: 2009-07High-strength structural bolting assemblies for preloading - Part 10: System HRC - Bolt and nut assemblies with calibrated preload; German version EN 14399-10:2009

DIN EN 24015 , Publication date: 1991-12Hexagon head bolts with reduced shank (shank diameter ≈ pitch diameter); product grade B (ISO 4015:1979); german version EN 24015:1991

DIN EN 27434 , Publication date: 1992-10Slotted set screws with cone point (ISO 7434:1983); german version EN 27434:1992

DIN EN 27435 , Publication date: 1992-10Slotted set screws with long dog point (ISO 7435:1983); german version EN 27435:1992

DIN EN 27436 , Publication date: 1992-10Slotted set screws with cup point (ISO 7436:1983); german version EN 27436:1992

DIN EN ISO 1207 , Publication date: 2011-10Slotted cheese head screws - Product grade A (ISO 1207:2011); German version EN ISO 1207:2011

DIN EN ISO 1479 , Publication date: 2011-10Hexagon head tapping screws (ISO 1479:2011); German version EN ISO 1479:2011

DIN EN ISO 1481 , Publication date: 2011-10Slotted pan head tapping screws (ISO 1481:2011); German version EN ISO 1481:2011

DIN EN ISO 1482 , Publication date: 2011-10Slotted countersunk (flat) head tapping screws (ISO 1482:2011); German version EN ISO 1482:2011

DIN EN ISO 1483 , Publication date: 2011-10Slotted raised countersunk (oval) head tapping screws (ISO 1483:2011); German version EN ISO 1483:2011

DIN EN ISO 1580 , Publication date: 2011-12Slotted pan head screws - Product grade A (ISO 1580:2011); German version EN ISO 1580:2011

DIN EN ISO 2009 , Publication date: 2011-12Slotted countersunk flat head screws - Product grade A (ISO 2009:2011); German version EN ISO 2009:2011

DIN EN ISO 2010 , Publication date: 2011-12Slotted raised countersunk head screws - Product grade A (ISO 2010:2011); German version EN ISO 2010:2011

DIN EN ISO 2342 , Publication date: 2004-05Slotted headless screws with shank (ISO 2342:2003); German version EN ISO 2342:2003

DIN EN ISO 4014 , Publication date: 2011-06Hexagon head bolts - Product grades A and B (ISO 4014:2011); German version EN ISO 4014:2011

DIN EN ISO 4016 , Publication date: 2011-06Hexagon head bolts - Product grade C (ISO 4016:2011); German version EN ISO 4016:2011

DIN EN ISO 4017 , Publication date: 2011-07Hexagon head screws - Product grades A and B (ISO 4017:2011); German version EN ISO 4017:2011

DIN EN ISO 4018 , Publication date: 2011-07Hexagon head screws - Product grade C (ISO 4018:2011); German version EN ISO 4018:2011

DIN EN ISO 4026 , Publication date: 2004-05Hexagon socket set screws with flat point (ISO 4026:2003); German version EN ISO 4026:2003

DIN EN ISO 4027 , Publication date: 2004-05Hexagon socket set screws with cone point (ISO 4027:2003); German version EN ISO 4027:2003

DIN EN ISO 4028 , Publication date: 2004-05Hexagon socket set screws with dog point (ISO 4028:2003); German version EN ISO 4028:2003

DIN EN ISO 4029 , Publication date: 2004-05Hexagon socket set screws with cup point (ISO 4029:2003); German version EN ISO 4029:2003

DIN EN ISO 4762 , Publication date: 2004-06Hexagon socket head cap screws (ISO 4762:2004); German version EN ISO 4762:2004

DIN EN ISO 4766 , Publication date: 2011-11Slotted set screws with flat point (ISO 4766:2011); German version EN ISO 4766:2011

DIN EN ISO 7045 , Publication date: 2011-12Pan head screws with type H or type Z cross recess - Product grade A (ISO 7045:2011); German version EN ISO 7045:2011

DIN EN ISO 7046-1 , Publication date: 2011-12Countersunk flat head screws (common head style) with type H or type Z cross recess - Product grade A - Part 1: Steel screws of property class 4.8 (ISO 7046-1:2011); German version EN ISO 7046-1:2011

DIN EN ISO 7046-2 , Publication date: 2011-12Countersunk flat head screws (common head style) with type H or type Z cross recess - Product grade A - Part 2: Steel screws of property class 8.8, stainless steel screws and non-ferrous metal screws (ISO 7046-2:2011); German version EN ISO 7046-2:2011

DIN EN ISO 7047 , Publication date: 2011-12Raised countersunk head screws (common head style) with type H or type Z cross recess - Product grade A (ISO 7047:2011); German version EN ISO 7047:2011

DIN EN ISO 7048 , Publication date: 2011-07Cross-recessed cheese head screws (ISO 7048:2011); German version EN ISO 7048:2011

DIN EN ISO 7049 , Publication date: 2011-11Cross-recessed pan head tapping screws (ISO 7049:2011); German version EN ISO 7049:2011

DIN EN ISO 7050 , Publication date: 2011-11Cross-recessed countersunk (flat) head tapping screws (ISO 7050:2011); German version EN ISO 7050:2011

DIN EN ISO 7051 , Publication date: 2011-11Cross-recessed raised countersunk (oval) head tapping screws (ISO 7051:2011); German version EN ISO 7051:2011

DIN EN ISO 7053 , Publication date: 2011-11Hexagon washer head tapping screws (ISO 7053:2011); German version EN ISO 7053:2011

DIN EN ISO 7380-1 , Publication date: 2011-11Button head screws - Part 1: Hexagon socket button head screws (ISO 7380-1:2011); German version EN ISO 7380-1:2011

DIN EN ISO 7380-2 , Publication date: 2011-11Button head screws - Part 2: Hexagon socket button head screws with collar (ISO 7380-2:2011); German version EN ISO 7380-2:2011

DIN EN ISO 8676 , Publication date: 2011-07Hexagon head screws with metric fine pitch thread - Product grades A and B (ISO 8676:2011); German version EN ISO 8676:2011

DIN EN ISO 8765 , Publication date: 2011-06Hexagon head bolts with metric fine pitch thread - Product grades A and B (ISO 8765:2011); German version EN ISO 8765:2011

DIN EN ISO 10510 , Publication date: 2011-07Tapping screw and washer assemblies with plain washers (ISO 10510:2011); German version EN ISO 10510:2011

DIN EN ISO 10642 [PLEASE NOTE: DOCUMENT WITHDRAWN] , Publication date: 2004-06Hexagon socket countersunk head screws (ISO 10642:2004); German version EN ISO 10642:2004

DIN EN ISO 10644 , Publication date: 2009-10Screw and washer assemblies made of steel with plain washers - Washer hardness classes 200 HV and 300 HV (ISO 10644:2009); German version EN ISO 10644:2009

DIN EN ISO 12474 , Publication date: 2011-01Hexagon socket head cap screws with metric fine pitch thread (ISO 12474:2010); German version EN ISO 12474:2010

DIN EN ISO 14579 , Publication date: 2011-06Hexalobular socket head cap screws (ISO 14579:2011); German version EN ISO 14579:2011

DIN EN ISO 14580 , Publication date: 2011-06Hexalobular socket cheese head screws (ISO 14580:2011); German version EN ISO 14580:2011

DIN EN ISO 14583 , Publication date: 2011-06Hexalobular socket pan head screws (ISO 14583:2011); German version EN ISO 14583:2011

DIN EN ISO 14584 , Publication date: 2011-06Hexalobular socket raised countersunk head screws (ISO 14584:2011); German version EN ISO 14584:2011

DIN EN ISO 14585 , Publication date: 2011-05Hexalobular socket pan head tapping screws (ISO 14585:2011); German version EN ISO 14585:2011

DIN EN ISO 14586 , Publication date: 2011-05Hexalobular socket countersunk head tapping screws (ISO 14586:2011); German version EN ISO 14586:2011

DIN EN ISO 14587 , Publication date: 2011-05Hexalobular socket raised countersunk (oval) head tapping screws (ISO 14587:2011); German version EN ISO 14587:2011

DIN EN ISO 15480 , Publication date: 2000-02Hexagon washers head drilling screws with tapping screw thread (ISO 15480:1999); German version EN ISO 15480:1999

DIN EN ISO 15482 , Publication date: 2000-02Cross recessed countersunk head drilling screws with tapping screw thread (ISO 15482:1999); German version EN ISO 15482:1999

Diagnostic Enzymology, 2nd Edition, 2014, Ed. by Kazmierczak, Steven / Azzazy, Hassan M. E., Series:De Gruyter Textbook, ISBN: 978-3-11-022780-2


Diagnostic Enzymology, 2nd Edition, 2014, Ed. by Kazmierczak, Steven / Azzazy, Hassan M. E., Series:De Gruyter Textbook, ISBN: 978-3-11-022780-2


Lançamento: Setembro de 2013

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

To be published: January 2014
Ed. by Kazmierczak, Steven / Azzazy, Hassan M. E.
Series:De Gruyter Textbook
ISBN: 978-3-11-022780-2
Paperback
Approx. xx, 300 pages
Language: English
Type of Publication: Textbook
Keywords: Enzymatic Analysis; Enzymatic Diagnostics; Enzymes; Laboratory Diagnostics; Marker

Aims and Scope

- 2nd improved and expanded edition of "Clinical Enzymology" (Lott/Wolf, 1987)
- Includes case studies and guidelines

This book is the 2nd improved and expanded edition of "Clinical Enzymology" (Lott/Wolf, 1987). It includes case studies and guidelines for specialists of laboratory medicine and clinicians, devotes each chapter to a specific enzyme or protein marker, contains case studies and guidelines, a section on marker biochemistry and physiology as well as a section on special pathology and analysis. The clear, didactic structure and the multiple choice questions also make the book valuable reading for graduate students in the fields of clinical pathology and laboratory medicine.

Grabb and Smith's Plastic Surgery, Seventh, 7th Edition, Charles H Thorne MD, LWW, Sep 9, 2013, ISBN 9781451109559, Hardbound


Grabb and Smith's Plastic Surgery, Seventh, 7th Edition, Charles H Thorne MD, LWW, Sep 9, 2013, ISBN 9781451109559, Hardbound

Lançamento: Setembro de 2013

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Author(s): Charles H Thorne  MD

Edition: Seventh
Product Format: Hardbound
ISBN: 9781451109559
Trim Size: 10.875 x 8.375
Pages: 976
Pub Date: Sep 9, 2013


Description


Grabb and Smith’s Plastic Surgery has long been considered the premier reference for plastic surgery residents and practitioners. So it should be no surprise that for this 7th edition major steps have been taken to completely revise and refresh its content.  As always, this single-volume reference covers all major areas of plastic and reconstructive surgery, including pediatric issues. But updates in this latest edition include a complete reworking of the section on the Hand, an expansion of the dermatology coverage, a new section on body contouring, and 11 new chapters; Principles of Awake Sedation, Otoplasty, Congenital Anomalies of the Breast, Brachioplasty and Upper Trunk Contouring, Principles of Plastic Surgery after Massive Weight Loss, Anesthetic Techniques in the Upper Extremity; Management of Mutiliating Injuries of the Upper Extremity, Hand Tumors, Vascular Disorders of the Upper Limb, Management of the Burned Hand, and Rheumatoid Arthritis and Atypical Arthritic Conditions of the Hand.


Features


• Chapters are short and high-yield
• Written by recognized experts, edited by a brand new editorial board
• Over 2,000 illustrations, including 1,500 in full-color
• Solution site 


Table of contents
 

PART 1: Principles, Techniques, and Basic Science 1 Techniques and Principles in Plastic Surgery . . . . . . . . 1 Charles H. Thorne 2 Wound Healing: Normal and Abnormal . . . . . . . . . 13 Geoffrey C. Gurtner and Victor W. Wong 3 Wound Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Donald W. Buck and Robert D. Galiano 4 The Blood Supply of the Skin and Skin Flaps . . . . . . 29 Geoffrey Ian Taylor, Russell J. Corlett, and Mark W. Ashton 5 Muscle Flaps and their Blood Supply . . . . . . . . . . . . 43 Jamie P. Levine 6 Transplantation Biology and Applications to Plastic Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Damon S. Cooney, Justin M. Sacks, Gerald Brandacher, and W. P. Andrew Lee 7 Implant Materials . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Timothy W. King 8 Principles of Microsurgery . . . . . . . . . . . . . . . . . . . . 70 Charles E. Butler and David M. Adelman 9 Principles and Techniques of Peripheral Nerve Repair, Grafts, and Transfers . . . . . . . . . . . . . . . . . . 77 Susan E. Mackinnon and Stephen H. Colbert 10 Tissue Expansion . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Ashley K. Lentz and Bruce S. Bauer 11 Principles of Office Sedation for Cosmetic Surgery . . . 94 Maximilian W. B. Hartmannsgruber, Dominick Cannavo, and Nikolaus Gravenstein 12 Local Anesthetics . . . . . . . . . . . . . . . . . . . . . . . . . . 100 Alisa C. Thorne part 2: Skin and Soft Tissue 13 Dermatology for Plastic Surgeons I—Skin care and Benign Dermatologic Conditions . . . . . . . . . . . 105 Renato Saltz and Bianca M. B. Ohana 14 Dermatology for Plastic Surgeons II—Cutaneous Malignancies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 Daniel J. Ceradini and Keith M. Blechman 15 Thermal, Chemical, and Electrical Injuries . . . . . . . 127 Matthew B. Klein 16 Principles of Burn Reconstruction . . . . . . . . . . . . . . 142 Matthias B. Donelan and Eric C. Liao 17 Radiation and Radiation Injuries . . . . . . . . . . . . . . 155 James Knoetgen III and Salvatore C. Lettieri David W. Low and Ivona Percec part 3: Congenital Anomalies and Pediatric Plastic Surgery 19 Cleft Lip and Palate: Embryology, Principles, and Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 Richard A. Hopper 20 Congenital Melanocytic Nevi . . . . . . . . . . . . . . . . . 200 Harvey Chim and Arun K. Gosain 21 Vascular Anomalies . . . . . . . . . . . . . . . . . . . . . . . . 206 Harvey Chim and Arun K. Gosain 22 Single-Suture Craniosynostosis and Deformational Plagiocephaly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221 Gary F. Rogers and Stephen M. Warren 23 Craniosynostosis Syndromes . . . . . . . . . . . . . . . . . . 232 Scott P. Bartlett and Christopher A. Derderian 24 Craniofacial Microsomia and Principles of Craniofacial Distraction . . . . . . . . . . . . . . . . . . . 241 Joseph G. McCarthy 25 Orthognathic Surgery . . . . . . . . . . . . . . . . . . . . . . . 252 Stephen B. Baker 26 Craniofacial Clefts and Hypertelorbitism . . . . . . . . 266 James P. Bradley and Henry K. Kawamoto 27 Ear Reconstruction . . . . . . . . . . . . . . . . . . . . . . . . . 283 Charles H. Thorne 28 Miscellaneous Craniofacial Conditions: Fibrous Dysplasia, Moebius Syndrome, Romberg Syndrome, Treacher Collins Syndrome, Dermoid Cyst, and Neurofibromatosis . . . . . . . . . . 295 Robert J. Havlik part 4: Head and Neck 29 Soft-Tissue and Skeletal Injuries of the Face . . . . . . 311 Larry H. Hollier Jr., Patrick Kelley, and John C. Koshy 30 Head and Neck Cancer and Salivary Gland Tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327 David M. Otterburn and Pierre B. Saadeh 31 Reconstruction of the Scalp, Calvarium, and Forehead . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342 J.Guilherme Christiano, Nicholas Bastidas, and Howard N. Langstein 32 Reconstruction of the Eyelids, Correction of Ptosis, and Canthoplasty . . . . . . . . . . . . . . . . . . 352 Nicholas T. Haddock 33 Nasal Reconstruction . . . . . . . . . . . . . . . . . . . . . . . 361 Evan Matros and Julian J. Pribaz 35 Reconstruction of the Cheeks . . . . . . . . . . . . . . . . . 384 Babak J. Mehrara 36 Facial Paralysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399 Julia K. Terzis and Katerina Anesti 37 Mandible Reconstruction . . . . . . . . . . . . . . . . . . . . 410 Joseph J. Disa and Evan Matros 38 Craniofacial and Maxillofacial Prosthetics . . . . . . . 420 George C. Bohle III, Cherry L. Estilo, and Joseph M. Huryn 39 Reconstruction of the Maxilla and Skull Base . . . . . 430 Eric G. Halvorson, Duc T. Bui, and Peter G. Cordeiro 40 Reconstruction of the Oral Cavity, Pharynx, and Esophagus . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 Matthew M. Hanasono part 5: Aesthetic Surgery 41 Skin Resurfacing . . . . . . . . . . . . . . . . . . . . . . . . . . . 451 Fritz E. Barton 42 Dermal and Soft-Tissue Fillers: Principles, Materials, and Techniques . . . . . . . . . . . . . . . . . . . 458 Z. Paul Lorenc 43 Botulinum Toxin . . . . . . . . . . . . . . . . . . . . . . . . . . 464 Michael A.C. Kane 44 Fat Grafting in Plastic Surgery . . . . . . . . . . . . . . . . 473 Louis P. Bucky, Ivona Percec, and Daniel Del Alexander Vecchio 45 Forehead and Brow Rejuvenation . . . . . . . . . . . . . . 480 Benjamin Z. Phillips, Erick A. Hoy, Johnny T. Chang, Jhonny Salomon, and Patrick K. Sullivan 46 Blepharoplasty . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487 Mark A. Codner and Renee M. Burke 47 Facelift . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501 Charles H. Thorne 48 Rhinoplasty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512 Jeffrey E. Janis, Jamil Ahmad, and Rod J. Rohrich 49 Otoplasty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530 Charles H. Thorne 50 Facial Skeletal Augmentation with Implants . . . . . . 537 Michael J. Yaremchuk and Chad R. Gordon 51 Osseous Genioplasty . . . . . . . . . . . . . . . . . . . . . . . . 544 Harvey M. Rosen 52 Hair Transplantation . . . . . . . . . . . . . . . . . . . . . . . 549 Carlos K. Wesley, Robin H. Unger, and Walter P. Unger part 6: Breast 53 Augmentation Mammaplasty: Principles, Techniques, Implant Choices, and Complications . . 565 Steven Alan Teitelbaum 54 Mastopexy and Mastopexy/Augmentation . . . . . . . 582 W. Grant Stevens, Andrea E. Van Pelt, and Adrian M. Przybyla Scott L. Spear 56 Vertical Reduction Mammaplasty . . . . . . . . . . . . . 603 Elizabeth J. Hall-Findlay 57 Gynecomastia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 Nolan S. Karp 58 Breast Cancer: Current Trends in Screening, Patient Evaluation, and Treatment . . . . . . . . . . . . . 620 Grant W. Carlson 59 Breast Reconstruction: Prosthetic Techniques . . . . . 625 Joseph J. Disa and Nima P. Patel 60 Latissimus Dorsi Flap Breast Reconstruction . . . . . 636 Dennis C. Hammond and Michael A. Loffredo 61 Breast Reconstruction: Tram Flap Techniques . . . . 643 James D. Namnoum 62 Breast Reconstruction: Free Flap Techniques . . . . . 649 Maurice Y. Nahabedian 63 Nipple Reconstruction . . . . . . . . . . . . . . . . . . . . . . 662 Michael S. Beckenstein 64 Congenital Anomalies of the Breast: Tuberous Breasts, Poland’s Syndrome, and Asymmetry . . . . . 668 Kenneth C. Shestak, Stephen Alex Rottgers, Lorelei J. Grunwaldt, Derrick Flethcher, and Angela Song Landfair part 7: Body Contouring 65 Liposuction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 679 Mary K. Gingrass 66 Abdominoplasty and Belt Lipectomy . . . . . . . . . . . 688 Al S. Aly and Emil J. Kohan 67 Lower Body Lift and Thighplasty . . . . . . . . . . . . . . 696 Joseph P. Hunstad and Remus Repta 68 Brachioplas

Fields Virology, 2 Volumes Set, Sixth , 6th Edition, Jun 17, 2013, David M. Knipe, Peter Howley, LWW, ISBN: 9781451105636, Hardbound


Fields Virology, 2 Volumes Set, Sixth , 6th Edition, Jun 17, 2013, David M. Knipe, Peter Howley, LWW, ISBN: 9781451105636, Hardbound

Prazo de entrega entre 3 a 4 semanas.

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Author(s): David M. Knipe  ,  Peter Howley 
Publication Date: Jun 17, 2013
Edition: SixthProduct
Format: Hardbound
ISBN: 9781451105636
Trim Size: 8.375 x 10.875
Pages: 2664Pub Date: Jun 17, 2013
Weight: 14.0

Description

Fields Virology is the authoritative reference book for virology, providing definitive coverage of all aspects of virology, including thorough coverage of virus biology as well as replication and medical aspects of specific virus families.  With the regular outbreaks of influenza, noroviruses as well as other emerging and re-emerging viruses it is essential to have the most up-to-date information available.With this Sixth Edition, all chapters have been completely updated, an important new emphasis has been placed on virus discovery and emerging viruses. Viruses associated with cancer, including the new human polyomaviruses, are highlighted in this Sixth Edition and new chapters have been added on circoviruses and mimiviruses. While the main focus of this edition continues to be on viruses, information on prions and the infectious spongiform encephalopathies are also included.

FEATURES

• 2-volume set
• Full color throughout with over 1,000 illustrations in total and most chapters provide key figures for use as lecture slides
• Online companion website with fully searchable text, all references linked to PubMed and additional material not found in the print for access to content anytime
• New coverage of emerging and viruses, including those causing influenza and HIV
• Updated coverage of viruses and cancer
• Coverage includes virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization
• Thorough coverage of all viruses of medical importance, including both basic science and clinical features 
• New chapters on circoviruses and mimiviruses and a new section on Chikungunya virus have been added 
• Important advances in antivirals, including new HCV protease inhibitors and HIV integrase inhibitors

Table of contents

SECTION I: GENERAL VIROLOGY   1 History of Virology Lynn W. Enquist and Vincent R. Racaniello   2 Principles of Virology Richard C. Condit   3 Principles of Virus Structure Stephen C. Harrison   4 Virus Entry and Uncoating Ari Helenius   5 Virus Replication Strategies Sean Whelan   6 Virus Assembly Eric Hunter   7 Viruses, Cell Transformation, and Cancer Daniel DiMaio and Hung Fan   8 Innate Responses to Viral Infections Akiko Iwasaki and Ruslan Medzhitov   9 Adaptive Immune Response to Viral Infections Thomas J. Braciale, Young S. Hahn, and Dennis R. Burton   10 Pathogenesis of Viral Infections Mark T. Heise and Herbert W. Virgin   11 Virus Evolution Edward C. Holmes   12 Epidemiology   13 Antiviral Agents Donald M. Coen and Douglas D. Richman   14 Immunization Against Viral Diseases Barney S. Graham, James E. Crowe, Jr., and Julie E. Ledgerwood   15 Diagnostic Virology and Virus Discovery Gregory A. Storch and David Wang   SECTION II: SPECIFIC VIRUS FAMILIES   Picornaviridae   16 Picornaviridae: The Viruses and Their Replication Vincent R. Racaniello   17 Enteroviruses Authors to come   18 Rhinoviruses James E. Gern and Ann C. Palmenberg   19 Hepatitis A Virus F. Blaine Hollinger and Annette Martin   Calciviridae   20 Caliciviridae: The Noroviruses Kim Y. Green   Astroviridae   21 Astroviruses Ernesto M\u00e9ndez and Carlos F. Arias   Togaviridae   22 Togaviridae Richard J. Kuhn   23 Alphaviruses Diane E. Griffin   24 Rubella Virus Tom Hobman   Flaviviridae   25 Flaviviridae Brett D. Lindenbach, Catherine L. Murray, Heinz-J\u00fcrgen Thiel, and Charles M. Rice   26 Flaviviruses Theodore C. Pierson and Michael S. Diamond   27 Hepatitis C Virus Stuart C. Ray, Justin R. Bailey, and David L. Thomas   Coronoviridae   28 Coronaviridae Paul S. Masters and Stanley Perlman   Arteriviridae   29 Arteriviruses Eric J. Snijder and Marjolein Kikkert   Order Mononegavirales   30 Mononegavirales Robert A. Lamb   Rhabdoviridae   31 Rhabdoviridae Douglas S. Lyles, Ivan V. Kuzmin, and Charles E. Rupprecht   Filoviridae   32 Filoviridae: Marburg and Ebola Viruses Heinz Feldmann, Anthony Sanchez, and Thomas W. Geisbert   Paramyxoviridae   33 Paramyxoviridae Robert A. Lamb and Griffith D. Parks   34 Parainfluenza Viruses Ruth A. Karron and Peter L. Collins   35 Mumps Virus Steven Rubin, Christian Sauder, and Kathryn Carbone   36 Measles Virus Diane E. Griffin   37 Henipaviruses Lin-Fa Wang, John S. Mackenzie, and Christopher C. Broder    38 Respiratory Syncytial Virus and Metapneumovirus Peter L. Collins and Ruth A. Karron   Bornaviridae   39 Bornaviridae Christiane Herden, Thomas Briese, W. Ian Lipkin, and J\u00fcrgen A. Richt   Orthomyxoviridae   40 Orthomyxoviridae Megan L. Shaw and Peter Palese   41 Orthomyxoviruses Peter F. Wright, Gabriele Neumann, and Yoshihiro Kawaoka   Bunyaviridae   42 Bunyaviridae Richard M. Elliott and Connie S. Schmaljohn   Arenaviridae   43 Arenaviridae Authors to come   Reoviridae   44 Orthoreoviruses Terence S. Dermody, John Parker, and Barbara Sherry   45 Rotaviruses Mary K. Estes and Harry B. Greenberg   46 Orbiviruses Polly Roy   Retroviridae   47 Retroviridae Stephen P. Goff   48 Human T Cell Leukemia Virus Types 1 and 2 Masahiro Fujii and Masao Matsuoka   49 Human Immunodeficiency Viruses: Replication   50 HIV-1: Pathogenesis, Clinical Manifestations, and Treatment Daniel R. Kuritzkes and Richard A. Koup   51 Nonhuman Lentiviruses David T. Evans, John H. Elder, and Ronald C. Desrosiers   52 Foamy Viruses Axel Rethwilm and Dirk Lindemann   Polyomaviridae   53 Polyomaviruses James A. DeCaprio, Michael J. Imperiale, Eugene O. Major   Papillomaviridae   54 Papillomaviruses Peter M. Howley, John C. Schiller, and Douglas R. Lowy   Adenoviridae   55 Adenoviridae Arnold J. Berk   56 Adenoviruses William S. M. Wold and Michael G. Ison   Parvoviridae   57 Parvoviridae Kenneth I. Berns and Colin R. Parrish   Circoviridae   58 Circoviridae Xiang-Jin Meng   Herpesviridae   59 Herpesviridae Philip E. Pellett and Bernard Roizman   60 Herpes Simplex Viruses Bernard Roizman, David M. Knipe, and Richard J. Whitley   61 Epstein-Barr Virus/Replication and Epstein-Barr Virus Richard Longnecker, Elliott Kieff, and Jeffrey I. Cohen   62 Cytomegaloviruses Edward S. Mocarski, Jr, Thomas Shenk, Paul Griffiths, and Robert F. Pass   63 Varicella-Zoster Virus Ann M. Arvin and Don Gilden Ann M. Arvin and Don Gilden   64 Human Herpesvirus 6 and 7 Koichi Yamanishi, Yasuko Mori, and Philip E. Pellett   65 Kaposi’s Sarcoma–Associated Herpesvirus Blossom Damania and Ethel Cesarman   Poxviridae   66 Poxviridae Bernard Moss   67 Poxviruses Inger K. Damon   Hepadnaviridae   68 Hepadnaviruses Cristoph Seeger, Fabien Zoulim, and William S. Mason   Genus Deltavirus   69 Hepatitis D John M. Taylor, Robert H. Purcell, and Patrizia Farci   Hepeviridae   70 Hepatitis E Virus Suzanne U. Emerson and Robert H. Purcell   Other Virus Groups   71 Mimi Viruses Philippe Colson and Didier Raoult   72 Plant Viruses W. Allen Miller and Steven A. Whitham   73 Insect Viruses Paul D. Friesen   74 Viruses and Prions of Yeasts, Fungi, and Unicellular Organisms Reed B. Wickner   75 Bacteriophages Roger W. Hendrix   Unclassified Agents   76 Prions Stanley B. Prusiner

International Directory of Arts 38th Edition, 2014, November 2013, De Gruyter Saur, ISBN: 978-3-11-030237-0


International Directory of Arts 38th Edition, 2014, November 2013, De Gruyter Saur, ISBN: 978-3-11-030237-0

Lançamento: Novembro de 2013

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

To be published: November 2013
8th Edition
ISBN: 978-3-11-030237-0
Approx. xxvi, 2900 pages
DE GRUYTER SAUR
Language: English
Type of Publication: Directory

Overview

- Unique reference directory which spotlights the entire art scene worldwide
 - museums or training sites as well as the art trade.
- The reader finds quickly the sought address and further information, thanks to the lucid and clear layout.


Aims and Scope

The 38th edition of International Directory of Arts (IDA) contains more about 150,000 addresses (including telephone and fax numbers, eMail and URL) from all over the world:

- Museums and Public Galleries
- Universities, Academies, Schools
- Associations
- Art and Antique Trade, Numismatics
- Art and Antiques Fairs
- Galleries- Auctioneers
- Restorers
- Art Publishers
- Art Journals
- Antiquarians and Art Booksellers

Within each chapter, addresses are arranged by country and within country, sections are set our alphabetically by city. Details of the specializations of museums, as well as the names of curators and senior academic museum staff are also included. The address contents were revised and updated for this edition following a questionnaire mailing. The revision also took into account numerous national and international reference works.The eBookPLUS format comprises the content and search criteria of the printed edition and its indices, facilitating complex searches.

British Pharmacopoeia - BP 2014 Print Package \ ISBN 9780113229352 \ August 2013


British Pharmacopoeia - BP 2014 Print Package \ ISBN 9780113229352 \ August 2013

Lançamento: Agosto de 2013

Prazo de entrega entre 3 a 4 semanas após lançamento:

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Author: The British Pharmacopoeia Commission Secretariat of the Medicines and Healthcare Products Regulatory

ISBN 9780113229352Size 6 x Volumes in slipcase 248 x 368 x 239mmFormat Hardback, CD-ROM, Online Access

British Pharmacopoeia 2014 publishes in August and is available to pre-order now.


Updated annually, the British Pharmacopoeia (BP) is the official, authoritative collection of standards for UK medicinal substances for human and veterinary use.The 2014 edition includes almost 3500 monographs which are legally enforced by the Human Medicines Regulations 2012. Where a pharmacopoeial monograph exists, medicinal products sold or supplied in the UK must comply with the relevant monograph. All monographs and requirements of the European Pharmacopoeia are also reproduced in the BP.

NEW FOR 2014

Agency (MHRA)

- 40 new British Pharmacopoeia monographs
- 272 amended monographs
- Three new BP Supplementary Chapters
- Four new BP (Vet) monographs
- One new BP (Vet) Supplementary Chapter
- All European Pharmacopoeia monographs integrated (7th Edition as amended by Supplements 7.1 to 7.8)

British Pharmacopoeia 2014 Print Package

- A six-volume printed edition, including a single volume of the BP (Veterinary) 2014
- A single-user CD-ROM
*A single-user licence to the online edition*
*These single-user licences are granted solely to the designated holder of the product within an organisation.

Practical Obstetrics, 21st Edition, Joachim W. Dudenhausen, De Gruyter, December 2013, ISBN: 978-3-11-027611-4 / Hardcover


Practical Obstetrics, 21st Edition, Joachim W. Dudenhausen, De Gruyter, December 2013, ISBN: 978-3-11-027611-4 / Hardcover

Prazo de entrega entre 3 a 4 semanas.

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.
Details

Joachim W. Dudenhausen
Founded by Pschyrembel, WillibaldIn collab. with Obladen, Michael / Grab, DieterTransl. by Travis, Susan E.

To be published: December 2013
ISBN: 978-3-11-027611-4
Approx. x, 475 pages
Language: English
Type of Publication: Specialist Text
Keywords: Obstetrics; Birth Complication; Obstetrical Surgery; Neonatology; Pregnancy Consultation; Pregnancy

Overview

- Completely updated proven classic
- Numerous concise and easy-to-remember phrases, practical tips
- More than 500 full color diagrams

Aims and Scope

A 21 ª edição deste livro de referência - agora publicado em inglês pela primeira vez - fornece informações práticas indispensáveis para a sala de parto, assim como para antes e depois do parto.

The 21st edition of this standard reference book – now published in English for the first time – provides indispensable, hands-on information for the delivery room, as well as before and after childbirth. The book combines proven facts and techniques with new insights through a consistent focus on practical and applied knowledge. All of those involved in the care of pregnant, laboring, and post natal women and newborn can benefit from the established didactic concept of this book.

Encyclopedia of Drug Metabolism and Interactions, 6-Volumes Set, Alexander V. Lyubimov (Editor), Wiley, ISBN: 978-0-470-45015-4, Hardcover, November 2012


Encyclopedia of Drug Metabolism and Interactions, 6-Volumes Set, Alexander V. Lyubimov (Editor), Wiley, ISBN: 978-0-470-45015-4, Hardcover, November 2012


Prazo de entrega entre 3 a 4 semanas.

O recebimento de encomendas internacionais está sujeito a procedimentos aduaneiros e isto pode causar atrasos além do tempo estimado de entrega.

Product Details

Alexander V. Lyubimov (Editor)
Hardcover: 4784 pages
Publisher: Wiley; 1 edition (November 5, 2012)
Language: English
ISBN-10: 0470450150
ISBN-13: 978-0470450154
Product Dimensions: 16.1 x 10.8 x 5.6 inches


Wiley is pleased to announce publication of the state-of-the-art, 6-volume Encyclopedia of Drug Metabolism and Interactions. This integrated reference collects otherwise scattered information on drug metabolism and interactions in one place for the first time. This book is a global effort, presenting more than 120 chapters by prominent authors from 11 different countries: USA, Canada, UK, Germany, Australia, Singapore, India, Japan, France, Denmark, and  Switzerland.

Drug metabolism is the process of drug modification by the body. Specifically, it involves the study of enzymes that biochemically modify the drugs, how different drugs interact within the body, and how genetic and non-genetic factors, including genetic polymorphism, age, gender, diet, and disease state affect the way the body processes drugs and how drugs interact with each other.  All of these factors mean that drug metabolism / interaction, and the chemical and biological aspects of metabolic transformations, are extremely important in new drug development.

The Encyclopedia of Drug Metabolism and Interactions discusses all preclinical, clinical, toxicological, chemical, regulatory, and marketing perspectives of drug metabolism and interactions. All aspects of drug metabolism and interactions are backed with a range of examples, in silico, in vitro, ex vivo, in laboratory animals, and in humans. The impact on drug metabolism of genetic differences and non-genetic factors, and of the types of enzymes that can be inhibited or induced, are described. This multi-volume encyclopedia also includes methods and detailed protocols describing how to perform studies of metabolism and drug interactions.

The Encyclopedia of Drug Metabolism and Interactions is an essential addition to all pharmaceutical, medical, and academic research libraries. Amongst the many users who will benefit from this 6-Volume Set are chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular biologists, and different levels of clinicians including practitioners and physicians. It is a must for researchers interested in all aspects of drug development.


Description


The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients.

This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover:

• Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models
• Effect of genetic differences and non-genetic factors on drug metabolism 
• Balance among drug metabolism, its inactivation/activation, and its potential toxicity
• Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans
• Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions.

This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians.


Table of Contents

VOLUME I
Part 1: Basics Overview of Drug Metabolism
Chapter 1 Review of Drug Metabolism in Drug Discovery and Development
Chapter 2 Reactions and Models of Drug Metabolism
Chapter 3 Enzyme kinetics of drug metabolism reactions and drug-drug interactions
Chapter 4 Developmental changes in drug metabolizing enzymes
Chapter 5 Species differences in drug metabolizing enzymes
Part II: Enzyme systems involved in drug metabolism and interactions in animals and humans
Chapter 6 Structure and function of cytochrome P450 enzymes
Chapter 7 Mechanism of cytochrome P450 mediated reactions
Chapter 8 Transcriptional regulation of cytochrome P450 enzymes
Chapter 9 Cytochrome P450 polymorphisms
Chapter 10 Flavin monooxygenase
Chapter 11 Molybdenum containing enzymes
Chapter 12 Amine odidases and reductases
Chapter 13 Epoxide hydrolase
Chapter 14 Esterases and amidases
Chapter 15 UDP- glucuronosyltransferases
Chapter 16 Sulfotransferases
Chapter 17 Glutathione S- transferases
Chapter 18 Amino acid conjugation

VOLUME II
Part III: General principals of ADME. Drug transporters and other mechanisms of transport
Chapter 1 Introduction to ADME. Overview
Chapter 2 Anatomical and Physiological Parameters that Influence Gastrointestinal Absorption
Chapter 3 Absorption of drugs into the body
Chapter 4 General principles of drug distribution
Chapter 5 ABC drug transporters and their impact on drug disposition/drug sensitivity and resistance
Chapter 6 SLC family transporters
Chapter 7 General principles of drug metabolism
Chapter 8 Systems where drug metabolism occurs
Chapter 9 Mass balance studies in animals and humans
Chapter 10 Bioavailability and bioequivalence
Chapter 11 Allometric scaling
Chapter 12 Effect of protein binding in ADME
Chapter 13 Excretion systems
Chapter 14 Pharmacokinetics (PK) and toxicokinetics (TK)
Chapter 15 Experimental design/mathematical models and data analysis/interpretation for PK /TK studies
Chapter 16 Physiologically-Based Pharmacokinetic Modeling
Chapter 17 Pharmacodynamics
Chapter 18 Interrelationships between Pharmacokinetics / Pharmacodynamics and metabolism
Part IV: ADME of some specific groups of drugs and delivery systems
Chapter 19 ADME of herbal and dietary constituents
Chapter 20 ADME of anticancer drugs
Chapter 21 ADME of cardiovascular drugs
Chapter 22 ADME of biological drugs
Chapter 23 ADME of natural toxins
Chapter 24 Metabolism and drug-drug interactions in pregnant mother/placenta/fetus

VOLUME III
Part V: Drug Design and development
Chapter 1 Where and when does drug metabolism enter as a concern?
Chapter 2 Challenges in frontloading toxicity testing of anti- cancer drugs in drug discovery
Chapter 3 Role of ADME for selection of new drug candidates
Chapter 4 Efficient drug development. How to speed up the development process
Chapter 5 Metabolite profiling and identification
Chapter 6 Bioactivation and oxidative stress
Chapter 7 Metabolism in drug safety evaluation
Part VI: Methods and protocols for prediction and evaluation of drug metabolism and drug interaction studies
Chapter 8 In silico models of drug metabolism and drug interactions
Chapter 9 Methods for determination of enzyme kinetics and metabolic rates
Chapter 10 Assays and microarrays for metabolic pathways
Chapter 11 Applications using Caco-2 cells and TC7 cells for drug metabolism studies
Chapter 12 In vitro liver systems to study induction/inhibition. Prediction of in vivo metabolism and drug-drug interactions
Chapter 13 Assessing the Hepatic Disposition and Toxicity of Xenobiotics Using Primary Hepatocytes
Chapter 14 Monoclonal Antibody Based Analyses of Human Drug Metabolism and Multifuctional Cytochromes P450
Chapter 15 Validation of precision- cut slices as a tool to study induction of drug metabolism
Chapter 16 Practical aspects of high throughput solubility and dissolution assessment in preformulation
Chapter 17 Integrated Approaches to Blood Brain Barrier and its role for drug metabolism and interactions
Chapter 18 In vivo models (not genetically modified)
Chapter 19 Using mouse knockout and transgenic models to study metabolism

VOLUME IV
Part VII: Pharmacology and toxicology
Chapter 1 Introduction. Overview. Role of metabolism in drug toxicity
Chapter 2 Bioactivation I: Phase I (P450)
Chapter 3 Bioactivation II: Phase I (non P450)
Chapter 4 Bioactivation III: Phase II
Chapter 5 Covalent Binding
Chapter 6 MIST
Chapter 7 Cell- based predictors for Toxicities of Metabolites
Chapter 8 Toxicogenomics
Chapter 9 Metabonomics
Chapter 10 Proteomics
Chapter 11 Stereoselectivity in drug metabolism
PART VIII: Influence of physiological conditions, diseases, drug- food interactions, age, sex, and other factors on drug metabolism and effect
Chapter 12 Genetic influence on metabolism
Chapter 13 Drug- Drug interactions 1: Inhibition
Chapter 14 Drug- Drug Interactions 2: Induction
Chapter 15 Ontogeny and Metabolism
Chapter 16 Natural Modulators of Human Drug Metabolism: Dietary supplements and their Clinical Relevance (Food Effects on Toxicity and Pharmacology)
Chapter 17 Idiosyncratic drug interactions
Chapter 18 Influence of inflammatory stress on drug (or xenobiotic) hepatotoxicity
Chapter 19 Regulation of Drug-Metabolizingnzymes and Transporters in Infection, Inflammation, and Cancer


VOLUME V
Part IX: Bioanalytical methods of studying metabolism
Chapter 1 Introduction. Importance of in vivo/in vitro analytical results in drug development Walter
Chapter 2 General principles of mass spectrometry: LC-MS, LC-MS/MS, and GC-MS
Chapter 3 Electrospray and Infusion nanospray ionization
Chapter 4 Emerging Atmospheric pressure ionization
Chapter 5 Matrix assisted laser desorption ionization (MALDI)
Chapter 6 Ion trap and quadrupole MS
Chapter 7 Hybrid LTQ- FTMS for Drug Metabolism Applications
Chapter 8 Mass Spectrometry Imaging (MSI)
Chapter 9 Ion Mobility Spectrometry and High Performance Tandem MS for metabolism studies and identification
Chapter 10 Inductively coupled plasma mass spectrometry (ICP MS) for element- containing drug metabolism analysis
Chapter 11 Online Electrochemical LC- MS Techniques for Profiling
Chapter 12 NMR
Chapter 13 Whole body autography and radioactive and non- radioactive isotope assays
Chapter 14 Ligand binding assays (immunoassays)
Chapter 16 Direct plasma analysis systems
Chapter 17 Analytical method development and validation in accordance to the regulatory guidelines
Chapter 18 Leveraging advances in HPLC to maximize DMPK data quality
Chapter 19 Methodologies to Increase Analytical Throughput
Chapter 20 Biomarkers to enable PK/PD
Chapter 21 Bioanalytics for Human Microdosing
Chapter 22 Bioactivation and Reactive Metabolite Assays
Chapter 23 Plasma protein binding

VOLUME VI
Part X: Clinical aspects of drug metabolism and interactions
Chapter 1 Overview and introduction. Role of drug metabolism and drug interactions in humans
Chapter 2 Human cytochrome P450 enzymes
Chapter 3 DDI Risk Assessment and Evaluation in Clinical Development: Interfacing Drug Metabolism and Clinical Pharmacology
Chapter 4 Current and future tools for predicting clinical drug interactions
Chapter 5 Predicting human biotransformation pathways
Chapter 6 Conjugation, transport, and elimination of drugs in humans
Chapter 7 Role and clinical consequences of human UDP- Glucuronosyltransferases
Chapter 8 Drug/food and drug/herb interactions
Chapter 9 Effects of disease on metabolism of drugs in humans
Chapter 10 Role of Phase I metabolism in drug activation and clinical treatment outcomes
Chapter 11 Role of metabolism in toxicity of drugs in humans
Chapter 12 Idiosyncratic drug reactions and the potential role of metabolism
Part XI Metabolism of specific drug groups and patient populations
Chapter 13 Metabolism of psychotropic drugs
Chapter 14 Metabolic-based consequences of polytherapy with AED
Chapter 15 Oral chemotherapeutic agents: Understanding mechanisms of action and drug interactions
Chapter 16 Drug metabolism and interactions in pediatric patients
Chapter 17 Population- based pharmacokinetic modeling and simulation
Chapter 18 Clinical Pharmacology in drug labeling. The impact of drug metabolism and clinical pharmacology on recommended dose of drugs